| 세션명 | 의료용 고분자 부문위원회(III) |
|---|---|
| 발표장 | 포스터장 |
| 논문코드 | 3PS-302 |
| 발표일 | 2018-10-12 |
| 발표시간 | 16:00-17:30 (게시시간: 14:00-17:30) |
| 논문제목 | Development of pathological stimulus-activatable nanoplatforms with theranostic functions. |
| 발표자 | 홍세리 |
| 발표자 소속 | 전북대학교 |
| 저자 | 홍세리, 선세미, 정은경, 이동원†, 이하늬 |
| 소속 | 전북대학교 |
| 논문초록 | Ultrasound imaging is one of the most commonly employed diagnostic modalities with CT, MRI and PET in clinics. Among them, ultrasound imaging allows accurate ultrasound imaging of organs in various diseases of cancerous lesions, inflammatory responses and cardiovascular pathologies with the assistance of contrast agents. However, microbubbles have several limitations for sensitive and specific molecular imaging. To overcome these limitations, there has been increasing interest in the development of pathological stimulus-activatable nanoplatforms with theranostic functions as an alternative to gas-filled microbubbles for contrast-enhanced ultrasound imaging. In this work, we developed acid-triggered bubble generating polymer nanoparticels for ultrasound imaging and targeted drug delivery using ketalized maltodextrin (KMD). We anticipate that KMD nanoparticles could serve as ultrasound imaging agents as well as drug carriers for various inflammatory diseases. |
THE POLYMER SOCIETY OF KOREA